Multiple flow channel particle analysis system

摘要

A microfluidic multiple channel particle analysis system which allows particles from a plurality of particle sources to be independently simultaneously entrained in a corresponding plurality of fluid streams for analysis and sorting into particle subpopulations based upon one or more particle characteristics.

主权项

1. A particle analysis system comprising:
a microfluidic chip including one or more flow channels, wherein each flow channel includes a detection region aligned to admit a beam of light into the detection region of the flow channel to detect a particle; at least one optical aperture optically associated with the detection region, the optical aperture having a leading edge and a trailing edge relative to the direction of flow; a first detector optically coupled to the detection region to receive at least one of light passing through or light emitted from the detection region, wherein the first detector generates a signal for the particle; and an analyzer configured to analyze the signal generated by the first detector to determine one or more ingress or egress event thresholds associated with the particle crossing the leading or trailing edges, respectively, of the optical aperture, and wherein the analyzer is configured to determine if the ingress or egress event thresholds satisfy a gate criteria.