Artificial blood vessel using decellularized blood vessel sheet

摘要

An artificial blood vessel that can be transplanted to blood vessels with a small diameter, can be adjusted to an arbitrary size of a diameter, improves in invasiveness when a graft is taken, and overcomes the problem on the provision of a graft is provided. An artificial blood vessel prepared from a decellularized tubular structure, which is prepared by processing a decellularized, sheet-like blood vessel (decellularized blood vessel sheet) into a roll structure, and a tissue adhesive, wherein a portion which is contacted with blood that flows within the artificial blood vessel consists of the tissue of the tunica intima lined with the tissue of the tunica media whereas a portion of the sheet that overlaps when the sheet is processed into a roll structure (overlap width) consists of the tissue of the tunica media and wherein a tissue adhesive is applied to the overlap width.

主权项

1. An artificial blood vessel prepared from a decellularized tubular structure, which is prepared by processing a decellularized blood vessel sheet into a roll structure, and a tissue adhesive, wherein a portion which is configured to be contacted with blood that flows within the artificial blood vessel comprises a tunica intima lined with a tunica media, wherein an overlap width portion of the sheet that overlaps when the sheet is processed into the roll structure consists of the tunica media, and wherein the tissue adhesive is applied to the overlap width portion.