| 发明名称 | Monoclonal antibodies directed to CD20 | ||
| 摘要 | The invention provides antibody to canine or feline or equine antigens. Specifically, antibodies directed to canine CD20 which have been caninized or felinized are provided. Also provided are methods for preparing high affinity antibodies to canine and feline CD20 as well as methods for treating B cell disorders in companion animals. | ||
| 申请公布号 | US9616120(B2) | 申请公布日期 | 2017.04.11 |
| 申请号 | US201113048135 | 申请日期 | 2011.03.15 |
| 申请人 | VET THERAPEUTICS, INC. | 发明人 | Hansen Genevieve |
| 分类号 | C07K16/28;A61K39/395;C07H21/00 | 主分类号 | C07K16/28 |
| 代理机构 | Hoxie & Associates LLC | 代理人 | Hoxie & Associates LLC |
| 主权项 | 1. An antibody or antibody fragment recognizing a canine or feline CD20, wherein said antibody or antibody fragment comprises a light chain comprising a sequence selected from SEQ ID NOs: 24, 25, and 39, and a heavy chain comprising a sequence selected from SEQ ID NOs: 23, and 38. | ||
| 地址 | Del Mar CA US | ||