| 发明名称 |
METHOD OF TREATING OVARIAN, TUBAL AND PERITONEAL CANCER |
| 摘要 |
A method of treating ovarian, tubal and peritoneal cancer is revealed. It comprises administering an effective amount of a pharmaceutical composition (including a copper chelator, a platinum-based chemotherapeutic agent and an anthracycline) to a subject in need thereof for reducing concentration of intracellular copper ions and promoting activation of transcription factor Sp1 and human copper transporter 1 (hCTR1). |
| 申请公布号 |
US2017095492(A1) |
申请公布日期 |
2017.04.06 |
| 申请号 |
US201514874937 |
申请日期 |
2015.10.05 |
| 申请人 |
NATIONAL CHENG KUNG UNIVERSITY ;NATIONAL CHENG KUNG UNIVERSITY HOSPITAL |
发明人 |
CHOU CHENG-YANG;KUO TIEN-EN;HUANG YU-FANG |
| 分类号 |
A61K31/704;A61K31/131;A61K31/555;A61K9/127 |
主分类号 |
A61K31/704 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating ovarian, tubal and peritoneal cancer, comprising administering an effective amount of a pharmaceutical composition to a subject in need of such treatment for reducing concentration of intracellular copper ions and promoting activation of transcription factor Sp1 and human copper transporter 1 (hCTR1), wherein the pharmaceutical composition comprises a copper chelator, a platinum-based chemotherapeutic agent and pegylated liposomal doxorubicin. |
| 地址 |
Tainan City TW |
