IBV STRAINS AND USES THEREOF

摘要

The present invention relates to novel infectious bronchitis virus strains and the uses thereof. The invention particularly relates to an inactivated or attenuated IBV, as well as to vaccine compositions comprising the same and the uses thereof to vaccinate avians. The invention also relates to nucleic acids, infected cells and methods for detecting the infectious bronchitis virus strains of the invention in any sample.

主权项

1. An attenuated Infectious Bronchitis Virus (IBV), wherein said IBV (i) comprises a S1 gene having a nucleotide sequence with at least 95% identity to SEQ ID NO: 1, or the complementary strand thereof and (ii) confers cross-protective immunity to at least two distinct IBV serotypes.