TRANSDERMAL FORMULATIONS OF PERGOLIDE AND USES THEREOF

摘要

This invention provides transdermal non-patch pergolide formulations useful for the treatment of disease in an equine. The invention also provides methods for treating a disease in an equine by administering a formulation of the invention to an equine.

主权项

1. A formulation comprising pergolide or a salt thereof, and a solvent system comprising one or more solvents selected from dimethyl sulfoxide, N-methylpyrrolidone, dimethylformamide, tetrahydrofuran, benzyl alcohol, acidic water, polypropylene glycol, methanol, a polyoxyethylene sorbitan monoester, water with about 40% of a cyclodextrin, dimethyl isosorbide, a caprylic/capric acid glyceride, or a suitable C8-C10 polyglycolized glyceride, wherein the solubility of said pergolide or salt thereof in said solvent system is 5 mg/ml or higher.