USE OF A N-ACETYLNEURAMINATE LYASE DERIVED FROM THE BACTERIUM ALIIVIBRIO SALMONICIDA IN THE PRODUCTION OF NEURAMINIC ACID AND DERIVATIVES THEREOF

摘要

The present invention provides to methods for the production of neuraminic acid or derivatives thereof under alkaline conditions and to the use of neuraminate lyases showing improved characteristics under alkaline conditions in the production of neuraminic acid or its derivatives. More particularly, the present invention employs inter alia a N-acetylneuraminate lyase which has been isolated from the psychrophilic bacterium Aliivibrio salmonicida LFI1238 and has shown to have improved characteristics under alkaline conditions.