发明名称 |
FORMULATIONS TARGETING IGFBP7 FOR DIAGNOSIS AND THERAPY OF CANCER |
摘要 |
The invention relates to antibodies or fragments thereof specific for insulin-like growth factor binding protein-7 (IGFBP7). A method of raising anti-IGFBP7 single domain antibodies is also disclosed and specific antibody clones are described, along with their binding characteristics. The anti-IGFBP7 antibodies may be useful as diagnostic tools for detecting neoplastic diseases involving tumor angiogenesis, and a variety of other angiogenesis associated diseases. |
申请公布号 |
EP2340262(B1) |
申请公布日期 |
2017.04.05 |
申请号 |
EP20090820151 |
申请日期 |
2009.10.14 |
申请人 |
National Research Council Canada |
发明人 |
STANIMIROVIC, Danica;ABULROB, Abedelnasser;MORENO, Maria |
分类号 |
C07K16/18;A61K39/395;A61K49/00;A61P35/00;G01N33/53;G01N33/574;G01N33/68 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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