发明名称 |
SOLUBLE PROTEIN CD5 OR CD6 FOR THE TREATMENT OF CANCER OR TUMOR OF FOR USE AS AN ADJUVANT |
摘要 |
The present invention discloses soluble isoforms of CD5 and CD6, which are scavenger-like lymphocyte receptors, for use in the prophylaxis or therapy of disorders or in therapeutic interventions, which would benefit from an exacerbated immune response to either endogenous or exogenous antigens, resulting from a decrease in lymphocyte subpopulations with regulatory functions and/or increase in lymphocyte subpopulations with effector functions. Special disorders are cell growth disorders, and chronic infections of bacterial, viral, fungal or parasitic origin. The invention also provides animal models for the study and the prophylaxis/treatment of autoimmune diseases, cancer, and chronic infections. |
申请公布号 |
EP2714066(B1) |
申请公布日期 |
2017.04.05 |
申请号 |
EP20120726052 |
申请日期 |
2012.05.29 |
申请人 |
Fundació Clínic per a la Recerca Biomèdica;Hospital Clinic i Provincial de Barcelona;Universitat de Barcelona |
发明人 |
LOZANO SOTO, Francisco;MARTÍNEZ, Vanessa Gabriela;FENUTRIA AUMESQUET, Rafael |
分类号 |
A61K38/17;A01K67/027;A61K31/475;A61K31/704;A61K39/39;A61P35/00;C07K14/705 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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