The invention concerns derivatives of CMAP27, which have a good antimicrobial activity and a low haemolytic activity as compared to the wild-type CMAP27 peptide. These derivatives can be used for antibiotic therapy or in a bacteriocidal composition. Further comprised in the invention is the use of CMAP27 and/or its derivatives as adjuvant.
申请公布号
EP3150627(A1)
申请公布日期
2017.04.05
申请号
EP20160197733
申请日期
2010.02.12
申请人
Universiteit Utrecht Holding B.V.
发明人
Bikker, Floris Jacob;van Dijk, Albert;Mars-Groenendijk, Rosalia;Veldhuizen, Edwin Johannes Adrianus;van der Kleij, Desiree;Haagsman, Hendrik;Molhoek, Elisabeth Margaretha
