| 摘要 |
This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof. |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
LAVEY, Brian, J.;KOZLOWSKI, Joseph, A.;ZHOU, Guowei;TONG, Ling;YU, Wensheng;WONG, Michael, K.C.;SHANKAR, Bandarpalle, B.;SHIH, Neng-Yang;SIDDIQUI, M., Arshad;ROSNER, Kristin, E.;DAI, Chaoyang;POPOVICI-MULLER, Janeta;GIRIJAVALLABHAN, Vinay, M.;LI, Dansu;MICULA, Aneta, M.;KIM, Seong-heon;YANG, De-yi;RIZVI, Razia |
