发明名称 |
CHIRAL DIAMINE COMPOUNDS FOR THE PREPARATION OF CHIRAL ALCOHOL AND CHIRAL AMINE |
摘要 |
A process for the stereoselective preparation of a chiral alcohol or a chiral amine, the process comprising reacting a first prochiral reactant selected from the group consisting of a ketone, an aldehyde, and an inline, with a second reactant comprising a Grignard reagent, in the presence of a chiral trans-diamim of formula (1) as defined herein. Also provided is the use of the chiral trans-diamine of formula (1) in a Grignard reaction and the chiral trans-diamines per se. |
申请公布号 |
EP3148978(A1) |
申请公布日期 |
2017.04.05 |
申请号 |
EP20150724310 |
申请日期 |
2015.05.26 |
申请人 |
UNIVERSITY COLLEGE DUBLIN |
发明人 |
GILHEANY, Declan;BIESZCZAD, Bartosz |
分类号 |
C07D311/76;C07C29/40;C07C211/36;C07C211/53;C07C215/50;C07C215/64;C07D235/12 |
主分类号 |
C07D311/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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