INTRAORALLY DISINTEGRABLE TABLET COMPRISING DISINTEGRABLE GRANULAR COMPOSITION

摘要

An object of the present invention is to provide an orally disintegrating tablet having both an excellent tablet hardness and disintegrability even when the content of a medicinal ingredient is high. This invention relates to an orally disintegrating tablet comprising a medicinal ingredient having distribution coefficient (logP) in a range of from -6.0 to 10.0 and a disintegrative particulate composition produced by granulation consisting of at least two stages, especially to said orally disintegrating tablet having tablet hardness of from 30 to 100 N, and disintegration time in water of from 10 to 30 sec.