摘要 |
Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R4, R5, X1, X2, X3 and X4 are as defined herein, and wherein the compound comprises at least one F, Cl, Br, I or 123I moiety, are provided. Uses of such compounds for imaging diagnostics in cancer and therapeutics methods for treatment of subjects in need thereof, including prostate cancer as well as methods and intermediates for preparing such compounds are also provided. |
申请人 |
British Columbia Cancer Agency Branch;The University of British Columbia |
发明人 |
ANDERSEN, Raymond John;GARCIA FERNANDEZ, Javier;JIAN, Kunzhong;SADAR, Marianne Dorothy;MAWJI, Nasrin R.;BANUELOS, Carmen Adriana;WANG, Jun;IMAMURA, Yusuke |