发明名称 PATHWAYS TO GENERATE AUDITORY HAIR CELLS
摘要 This disclosure relates to methods and compositions for modulating (e.g., increasing) Atoh1 activity (e.g., biological activity) and/or expression (e.g., transcription and/or translation) in vivo and/or in vitro, e.g., in a biological cell and/or in a subject. The methods and compositions described herein can be used in the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression in a biological cell.
申请公布号 EP2381936(B1) 申请公布日期 2017.04.05
申请号 EP20090828380 申请日期 2009.11.24
申请人 Massachusetts Eye & Ear Infirmary 发明人 EDGE, Albert;SHI, Fuxin
分类号 A61K31/16;A61K35/54;A61K38/17;A61K38/43;A61K45/06;A61P27/16 主分类号 A61K31/16
代理机构 代理人
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