| 发明名称 |
Use of a thiazolo pyrimidinone for the treatment of inflammatory bowel disease |
| 摘要 |
Present invention relates to a low dose pharmaceutical composition, preferably oral composition comprising therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid (compound A) in the range of 2.5 mg to 60 mg. Present invention also relates to a method of treating inflammatory bowel disease in a mammal by administrating said low dose pharmaceutical composition. Further, present invention relates to a use of the compound A for the preparation of low dose pharmaceutical composition for the treatment of inflammatory bowel disease in a mammal. |
| 申请公布号 |
US9610247(B2) |
申请公布日期 |
2017.04.04 |
| 申请号 |
US201414890131 |
申请日期 |
2014.05.12 |
| 申请人 |
Torrent Pharmaceuticals Limited |
发明人 |
Dutt Chaitanya;Chauthaiwale Vijay;Gupta Ram;Zambad Shitalkumar;Deshpande Shailesh;Kotecha Jignesh;Gupta Ramesh;Srivastava Sanjay;Chhipa Laxmikant;Abraham Jaya |
| 分类号 |
A61K31/519;A61K9/00;A61K9/20;A61K9/28 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
Evans Daniel R.;Hayworth Melissa M. |
| 主权项 |
1. A method of treating inflammatory bowel disease in a human, the method comprising administering to the human a pharmaceutical composition comprising a therapeutically effective amount of [(2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diaza-benzo[a]azulene-3-carbonyl)-amino]-acetic acid (“Compound A”) or its pharmaceutically acceptable salt,
wherein the therapeutically effective amount of Compound A ranges from 2.5 mg to 60 mg. |
| 地址 |
Ahmedabad IN |
