发明名称 |
Formulations comprising triptan compounds |
摘要 |
The invention provides a pharmaceutical composition for intranasal administration comprising a salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. Other aspects and embodiments are contemplated and described.;The invention also provides a pharmaceutical composition for intranasal administration comprising a triptan, a pharmaceutically acceptable vehicle and a mucosal permeation enhancer, wherein upon said administration said composition provides a Tmax substantially equivalent to subcutaneous administration of said triptan. Other aspects and embodiments are contemplated and described. |
申请公布号 |
US9610280(B2) |
申请公布日期 |
2017.04.04 |
申请号 |
US201514925564 |
申请日期 |
2015.10.28 |
申请人 |
DR. REDDY'S LABORATORIES LIMITED |
发明人 |
Gandhi Rajesh;Manikonda Sreekanth;Jana Arun;Kunte Sameer Shrinivas |
分类号 |
A61K31/404;A61K31/40;A61K31/70;A61K31/7028;A61K9/00;A61K45/06 |
主分类号 |
A61K31/404 |
代理机构 |
Pergament & Cepeda LLP |
代理人 |
Pergament & Cepeda LLP ;Cepeda Milagros A.;Pergament Edward D. |
主权项 |
1. A method of treating a human suffering from or susceptible to cephalic pain comprising intranasal administration of a composition comprising of an aqueous solution of a citric acid salt of sumatriptan or a physiologically acceptable solvate thereof, an alkyl glycoside or saccharide alkyl ester and optionally at least one pharmaceutically acceptable excipient, wherein the said composition provides Tmax value of less than 30 minutes upon said administration. |
地址 |
Hyderabad IN |