| 发明名称 | Methods of reducing the risk of a cardiovascular event in a subject on statin therapy | ||
| 摘要 | In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof. | ||
| 申请公布号 | US9610272(B2) | 申请公布日期 | 2017.04.04 |
| 申请号 | US201615333991 | 申请日期 | 2016.10.25 |
| 申请人 | Amarin Pharmaceuticals Ireland Limited | 发明人 | Soni Paresh |
| 分类号 | A61K31/232;A61K31/397;A61K45/06 | 主分类号 | A61K31/232 |
| 代理机构 | Perkins Coie LLP | 代理人 | Perkins Coie LLP |
| 主权项 | 1. A method of reducing a risk of cardiovascular death and/or unstable angina in a subject on statin therapy, the method comprising administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of ethyl icosapentate per day, wherein the subject has a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL and optionally has established cardiovascular disease. | ||
| 地址 | Dublin IE | ||