发明名称 |
Substituted tricyclic compounds as FGFR inhibitors |
摘要 |
The present invention relates to tricyclic compounds, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer. |
申请公布号 |
US9611267(B2) |
申请公布日期 |
2017.04.04 |
申请号 |
US201313915775 |
申请日期 |
2013.06.12 |
申请人 |
Incyte Holdings Corporation;Incyte Corporation |
发明人 |
Wu Liangxing;Zhang Colin;He Chunhong;Lu Liang;Yao Wenqing |
分类号 |
C07D471/14;C07D471/20;C07D471/22;C07D495/14;C07D498/14;C07D498/22;C07D491/22 |
主分类号 |
C07D471/14 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A compound which is 3-(2, 6-difluoro-3,5-dimethoxyphenyl)-1 -ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one, or a pharmaceutically acceptable salt thereof. |
地址 |
Wilmington DE US |