| 发明名称 | Truncated secretory aspartyl proteinase 2 | ||
| 摘要 | The present invention relates to an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. The present invention also relates to a composition comprising an isolated truncated form of the secretory aspartyl proteinase 2, as well as to nucleic acid molecules encoding same. | ||
| 申请公布号 | US9610334(B2) | 申请公布日期 | 2017.04.04 |
| 申请号 | US201414219163 | 申请日期 | 2014.03.19 |
| 申请人 | Istituto Superiore di Sanita;NovaDigm Therapeutics, Inc. | 发明人 | Zurbriggen Rinaldo;De Bernardis Flavia;Cassone Antonio;Rasi Silvia |
| 分类号 | A61K39/002;A61K38/00;A61K39/00;G01N33/573;C12N9/64;C12Q1/68 | 主分类号 | A61K39/002 |
| 代理机构 | Saul Ewing LLP | 代理人 | Saul Ewing LLP ;Doyle Kathryn;Silva Domingos J. |
| 主权项 | 1. An immunogenic composition comprising an effective amount of an isolated polypeptide comprising an amino acid sequence at least 95% identical to SEQ ID NO: 1 over the entire length of SEQ ID NO: 1, wherein the polypeptide is fewer than 342 amino acids in length and an effective amount of a heterologous immune-stimulatory protein, wherein the immunogenic composition is formulated as a sterile solution. | ||
| 地址 | Rome IT | ||