| 发明名称 | Therapeutic and/or preventive agent comprising 1-indansulfamide derivative for pain | ||
| 摘要 | The present invention is directed to a method of treating pain comprising the administering the following 1-indansulfamide compounds: N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (−)-N-(7-chloro-2,2,5-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, N-[(1S)-2,2-difluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, and N-[(1S)-2,2,5-trifluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide. | ||
| 申请公布号 | US9610262(B2) | 申请公布日期 | 2017.04.04 |
| 申请号 | US201415102046 | 申请日期 | 2014.12.17 |
| 申请人 | Eisai R&D Management Co., Ltd. | 发明人 | Higashiyama Hiroyuki;Kazuta Yuji;Hashimoto Keisuke |
| 分类号 | A61K31/165;A61K31/18 | 主分类号 | A61K31/165 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A method of treating pain in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound selected from the group consisting of (1) N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (2) (−)-N-(7-chloro-2,2,5-trifluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, (3) N-[(1S)-2,2-difluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide, and (4) N-[(1S)-2,2,5-trifluoro-7-methyl-2,3-dihydro-1H-inden-1-yl]sulfamide or a pharmaceutically acceptable salt thereof. | ||
| 地址 | Tokyo JP | ||