发明名称 Personalizing substance for application to the skin or addition to tattoo ink and methods of preparation thereof
摘要 Compositions for delivering materials, such as a biological material, sand, soil, metal, water, sea water, holy water, synthetic or biological polymers, cremated ash, ceramics, animal or plant tissue, or another physiologically compatible component having personal significance to an individual are described herein. The material(s) are encapsulated in an inert, non-bioerodible, hydrophobic, polymeric material. Methods of making microparticles encapsulating the personalizing substance and methods of use are also provided. The personalizing substance may be encapsulated in a polymeric non-bioerodible microparticle. The encapsulated personalizing substance may be combined with a carrier for delivery to an individual's skin. In some embodiments, the personalizing substance is added to a tattoo ink and incorporated in a tattoo created on an individual's skin. Following injection in the skin, the encapsulated material remains in the microparticles, and is not released over time.
申请公布号 US9610229(B2) 申请公布日期 2017.04.04
申请号 US201514593409 申请日期 2015.01.09
申请人 Chamber Works, LLC 发明人 Duffy Patrick;Jorgensen Ellen Dias;Boger Erich;Mathiowitz Edith
分类号 A61K8/02;A61K8/11;A61K8/60;A61K8/81;A61Q1/02 主分类号 A61K8/02
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP
主权项 1. A composition comprising DNA encapsulated in a non-bioerodible, polymeric microparticle, wherein: (a) the microparticle comprises a biocompatible, hydrophobic, non-bioerodible polymer; (b) the microparticle does not comprise silica; (c) the microparticle does not release a detectable amount of the DNA for at least one year after delivery to an individual's skin; and (d) the microparticle comprises up to 0.01% (w/w) DNA.
地址 Wilmington DE US