| 摘要 |
A method is disclosed for making a pharmaceutical composition for pulmonary administration, the method comprising a step in which an inhalable pharmaceutically active material is acoustically blended in a resonant acoustic blender, wherein the pharmaceutical composition is for localised pulmonary administration, and wherein the pharmaceutically active material is selected from budesonide, formoterol fumarate, glycopyrronium bromide, indacaterol maleate, umeclidinium bromide, vilanterol trifenatate, tiotropium bromide, salmeterol xinafoate or fluticasone propionate, and wherein the pharmaceutical composition comprises a particulate excipient material such as alpha-lactose monohydrate in particulate form. |
