发明名称 |
Bicyclic pyridinones useful as gamma secretase modulators |
摘要 |
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. The compounds of the invention are useful as gamma secretase modulators and for the treatment of neurodegeneration and psychiatric disorders, including Alzheimer’s Disease or Niemann-Pick type C disease. |
申请公布号 |
NZ704863(A) |
申请公布日期 |
2017.03.31 |
申请号 |
NZ20130704863 |
申请日期 |
2013.09.06 |
申请人 |
PFIZER INC. |
发明人 |
O’donnell Christopher John;Am Ende Christopher William;Green Michael Eric;Johnson Douglas Scott;Kauffman Gregory Wayne;Patel Nandini Chaturbhai;Pettersson Martin Youngjin;Stiff Cory Michael;Subramanyam Chakrapani;Tran Tuan Phong;Stepan Antonia Friederike;Verhoest Patrick Robert |
分类号 |
C07D471/04;A61K31/4985;A61P25/28 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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