发明名称 |
IMPROVED STABILITY OF LIPOSOME FORMULATIONS AND USES THEREOF |
摘要 |
The present invention provides improved stable liposomal formulations and method of preparation thereof. The liposomal formulations include liposomes containing a phosphatidylcholine lipid, a sterol, a PEG-lipid, and a taxane, wherein the taxane is docetaxel or a derivative thereof. The liposomal formulations have improved stability and extended shelf-life. The present invention also provides pharmaceutical compositions comprising a liposomal formulation for the treatment of cancer. |
申请公布号 |
WO2017053464(A1) |
申请公布日期 |
2017.03.30 |
申请号 |
WO2016US52932 |
申请日期 |
2016.09.21 |
申请人 |
MALLINCKRODT LLC |
发明人 |
PODARALLA, Satheesh;LAI, Tsz Chung;YUE, Baohua |
分类号 |
A61K9/00;A61K9/127;A61K31/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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