发明名称 |
UMBILICAL TISSUE COMPOSITIONS AND METHODS OF USE |
摘要 |
Disclosed are compositions comprising umbilical tissue, wherein the umbilical tissue comprises one or more engineered channels. Also disclosed are compositions comprising a previously cryopreserved umbilical tissue, wherein after cryopreservation and subsequent thawing the umbilical tissue comprises: a) viable cells native to the umbilical tissue,; b) tissue integrity of native umbilical tissue; c) one or more growth factors that are native to the umbilical tissue; and d) depleted amounts of one or more types of functional immunogenic cells. Disclosed are methods of producing compositions comprising umbilical tissue, wherein the umbilical tissue comprises one or more engineered channels. Also disclosed are methods of treating damaged tissue comprising administering to the site of the damaged tissue compositions comprising umbilical tissue, wherein the umbilical tissue comprises one or more engineered channels. |
申请公布号 |
WO2017053701(A1) |
申请公布日期 |
2017.03.30 |
申请号 |
WO2016US53309 |
申请日期 |
2016.09.23 |
申请人 |
OSIRIS THERAPEUTICS, INC. |
发明人 |
DANILKOVITCH, Alla;DUAN-ARNOLD, Yi;MOORMAN, Matthew;LERCH, Anne;KUANG, Jin-Qiang |
分类号 |
A61K35/50;A61K38/17 |
主分类号 |
A61K35/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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