发明名称 |
XYLOSE UTILIZING OLEAGINOUS YEAST |
摘要 |
Presented herein are oleaginous strains of yeast such as Saccharomyces cerevisiae that have been modified to allow for xylose utilization. Such strains are also modified to allow for higher lipid accumulation utilizing a broad range of sugar monomers such as those released during pretreatment and enzymatic saccharification of lignocellulosic biomass. Methods of producing lipids and ethanol using these yeast strains are also disclosed. |
申请公布号 |
US2017088866(A1) |
申请公布日期 |
2017.03.30 |
申请号 |
US201615282591 |
申请日期 |
2016.09.30 |
申请人 |
Alliance for Sustainable Energy, LLC |
发明人 |
KNOSHAUG Eric P.;ZHANG Min;SINGH Arjun;GUARNIERI Michael T. |
分类号 |
C12P7/64;C12N9/12;C12N15/81;C12N9/10;C12P7/06;C12N9/04;C07K14/395 |
主分类号 |
C12P7/64 |
代理机构 |
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代理人 |
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主权项 |
1. An engineered yeast cell, comprising exogenously added genes encoding xylose reductase, xylitol dehydrogenase and xylulose kinase enzymes; wherein the snfl gene of the yeast cell has been ablated; and wherein the yeast cell has been modified to express the GAL2 transporter in the presence of glucose. |
地址 |
Golden CO US |