TREATMENT OF NEUROTRAUMA USING ANTIBODIES TO LYSOPHOSPHATIDIC ACID

摘要

Methods are provided for treating neurotrauma, for example, traumatic brain injury (TBI), using antibodies and antibody fragments that bind lysophosphatidic acid (LPA). Such treatment may result in functional locomotor recovery in subjects so treated, as well as reducing the size of a brain infarct in subjects having or suspected of having sustained neurotrauma such a TBI.

主权项

1. A method of treating neurotrauma in a subject comprising administering to said subject a therapeutically effective amount of an antibody, or a fragment thereof, that binds lysophosphatidic acid, thereby treating the neurotrauma.