发明名称 METHODS FOR TREATING DIFFUSE LARGE B-CELL LYMPHOMA AND THE USE OF BIOMARKERS AS A PREDICTOR OF RESPONSIVENESS TO DRUGS
摘要 In one aspect, provided herein are methods for predicting the responsiveness of DLBCL patients to treatment with lenolidomide or Compound A; or a stereoisomer thereof; or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate thereof; or a polymorph thereof utilizing biomarkers or classfiers that correlate with responsiveness to one of these drugs. In another aspect, provided herein are methods for treating a DLBCL patient determined to be responsive to treatment with lenolidomide or Compound A; or a stereoisomer thereof; or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate thereof; or a polymorph thereof utilizing biomarkers or classifiers (or output thereof) that correlate with responsiveness to one of these drugs.
申请公布号 WO2017053555(A1) 申请公布日期 2017.03.30
申请号 WO2016US53092 申请日期 2016.09.22
申请人 CELGENE CORPORATION 发明人 TROTTER, Matthew William, Burnell;RISUENO-PEREZ, Alberto;POURDEHNAD, Michael;GANDHI, Anita;HAGNER, Patrick
分类号 A61K31/454;A61K31/517;A61K31/5377 主分类号 A61K31/454
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