发明名称 |
CELLS AND METHOD OF CELL CULTURE |
摘要 |
The invention relates to a method of cell culture where the cells are modified to reduce the level of synthesis of growth and/or productivity inhibitors by the cell. The invention also relates to a method of cell culture for improving cell growth and productivity, in particular in fed-batch culture of mammalian cells at high cell density. The invention further relates to a method of producing cells with improved cell growth and/or productivity in cell culture and to cells obtained or obtainable by such methods. |
申请公布号 |
WO2017051347(A2) |
申请公布日期 |
2017.03.30 |
申请号 |
WO2016IB55666 |
申请日期 |
2016.09.22 |
申请人 |
PFIZER INC. |
发明人 |
HILLER, Gregory Walter;MITCHELL, Jeffrey Joseph;MULUKUTLA, Bhanu Chandra;PEGMAN, Pamela Mary |
分类号 |
C12P21/00;C07K14/435;C07K16/00 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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