| 主权项 |
1. A compound of formula I, or a pharmaceutically acceptable salt or co-crystal thereof, wherein: m represents an integer selected from 0, 1 and 2; R1=R3=R4 and represents H; R2 represents H, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy or C1-C6 haloalkoxy; n represents an integer selected from 0 and 1; R5 represents C3-C7 cycloalkyl or phenyl, which C3-C7 cycloalkyl or phenyl is unsubstituted or substituted by one or two halo, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy or C1-C6 haloalkoxy groups; R6 represents H, C1-C6 alkyl or C1-C6 haloalkyl, which C1-C6 alkyl is unsubstituted or substituted by one or two C1-C6 alkoxy or C1-C6 haloalkoxy groups; R7 represents H, C1-C6 alkyl or C1-C6 haloalkyl, which C1-C6 alkyl is unsubstituted or substituted by one or two C1-C6 alkoxy or C1-C6 haloalkoxy groups; X represents a group —C(H)R9—, —O— or —S—; R8 represents H and R9 represents H; or R8 and R9 form a fused cyclopropyl ring which is unsubstituted or substituted by 1,1-dichloro; with the proviso that the compounds N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4,5-dihydronaphtho[2,1-d]isoxazole-3-carboxamide and N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-7-methoxy-4,5-dihydronaphtho[2,1-d]isoxazole-3-carboxamide are excluded. |
