发明名称 |
TREATMENT AND PREVENTION OF NEURONAL CELL LOSS USING L-ORNITHINE IN COMBINATION WITH AT LEAST ONE OF PHENYLACETATE AND PHENYLBUTYRATE |
摘要 |
Disclosed herein are methods of treating and preventing neuronal cell loss in a subject using ornithine in combination with phenylacetate or phenylbutyrate. In some embodiments, the subject has received or will receive a surgical procedure (for example, liver transplantation) for treating a liver disease. In some embodiments, the subject suffers from a liver disease and hypotension. |
申请公布号 |
WO2017053613(A1) |
申请公布日期 |
2017.03.30 |
申请号 |
WO2016US53176 |
申请日期 |
2016.09.22 |
申请人 |
OCERA THERAPEUTICS, INC. |
发明人 |
ROSE, Christopher, F.;CLEMENT, Marc-André;BOSOI, Cristina, R.;OLIVEIRA, Mariana, Macedo;TREMBLAY, Melanie;BEMEUR, Chantal |
分类号 |
A61K31/198;A61K31/192;A61K31/195;A61P1/16;A61P25/00 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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