| 发明名称 |
Methods and Compositions for Synthesizing Improved Silk Fibers |
| 摘要 |
The present disclosure provides methods and compositions for directed to synthetic block copolymer proteins, expression constructs for their secretion, recombinant microorganisms for their production, and synthetic fibers (including advantageously, microfibers) comprising these proteins that recapitulate many properties of natural silk. The recombinant microorganisms can be used for the commercial production of silk-like fibers. |
| 申请公布号 |
US2017088675(A1) |
申请公布日期 |
2017.03.30 |
| 申请号 |
US201615285256 |
申请日期 |
2016.10.04 |
| 申请人 |
Bolt Threads, Inc. |
发明人 |
Widmaier Daniel M.;Breslauer David N.;Kittleson Joshua;Turner Brendan;Wray Lindsay |
| 分类号 |
C08H1/00;B29C47/00;B29C47/88;D01F11/02;D01F6/68;D01D1/02;D01D5/00;C07K14/435;D01F4/02 |
主分类号 |
C08H1/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A fiber spinning solution, comprising
a polypeptide, the polypeptide comprising from 2 to 8 concatenated repeats of SEQ ID NO: 1396 or circularly permuted variants thereof, the polypeptide further comprising a FLAG tag; and a spinning solvent, wherein said polypeptide is dissolved in said spinning solvent. |
| 地址 |
Emeryville CA US |
