CHIMERIC PLANT BASED VIRUS-LIKE-PARTICLES, AND USES THEREOF

摘要

The present disclosure provides chimeric virus-like-particles (VLPs) based on non- human pathogenic plant viruses, which can be used for virus mediated delivery of cargo molecules, such as antibodies. In particular, the instant disclosure provides various chimeric VLPs based on the Sesbania mosaic virus or the Pepper vein banding 10 virus fused with domains from the SpA protein from Staphylocccus.