METHOD FOR OBTAINING A COMPOSITE COATING ON TITANIUM IMPLANTS FOR TISSUE ENGINEERING

摘要

A composite coating and method for preparing the composite coating on titanium implants for tissue culture and tissue engineering is provided. The implants are characterized in that the titanium component to be coated is placed in a aqueous solution containing calcium cations, phosphate anions, and dispersed carbon nanoparticles (such as single layer graphene oxide or graphene oxide) in an amount of about 0.05%-1.50% by weight relative to the total weight of aqueous solution. The dimensions of the dispersed graphene oxide should be around, but not limited to, 300-800 nm (X-Y), while their thickness is about 0.7-1.2 nm. The aqueous solution with carbon nanoparticles is prepared by mixing for at least 72 h in temperature in range 20-35° C. and sonicated before electrodeposition process. In the prepared solution is further placed titanium which acts as cathode element (may be the implant), and anode which can be, for example, a platinum rod. Between the cathode and anode is set a potential from −1.3V to −1.7V which results in coating formation by electrodeposition. The titanium implant before the electrodeposition process is treated in sodium hydroxide of HF to improve coating formation and thickness.

主权项

1. A method for preparing a composite coating on an implant comprising:
providing an aqueous electrolytic solution, wherein the aqueous electrolytic solution comprises calcium cations, phosphate anions, and dispersed carbon nanoparticles; placing the implant into the aqueous electrolytic solution; and applying a voltage between a cathode and anode for electrodeposition of the calcium cations, phosphate anions, and dispersed carbon nanoparticles onto the implant.