| 发明名称 |
TUBULYSIN COMPOUNDS, METHODS OF MAKING AND USE |
| 摘要 |
Tubulysin compounds of the formula (I) where R1, R2, R3a, R3b, R4, R5, W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety. |
| 申请公布号 |
EP2956173(B1) |
申请公布日期 |
2017.03.29 |
| 申请号 |
EP20140706743 |
申请日期 |
2014.02.10 |
| 申请人 |
Bristol-Myers Squibb Company |
发明人 |
CHENG, Heng;CONG, Qiang;GANGWAR, Sanjeev |
| 分类号 |
A61K47/68;A61P35/00;C07K5/078 |
主分类号 |
A61K47/68 |
| 代理机构 |
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