发明名称 |
NOVEL BIOMARKERS FOR ACUTE MYELOID LEUKEMIA |
摘要 |
Methods for the diagnosis of leukemias, and more specifically AML, such as MLL-AF9 AML, in a subject, based on the assessment of the expression or activity of one or more of the genes listed in Tables 1 and 2 are disclosed. The use of antibodies or antigen-binding fragments thereof that bind to one or more of proteins showing preferential expression at the cell surface of AML leukemic cells for treating AML is also disclosed. |
申请公布号 |
EP2992331(A4) |
申请公布日期 |
2017.03.29 |
申请号 |
EP20140791102 |
申请日期 |
2014.04.30 |
申请人 |
Université de Montréal;Université Laval |
发明人 |
WILHELM, Brian Thomas;BARABÉ, Frédéric |
分类号 |
G01N33/574;A61K39/395;A61P35/02;C12Q1/68;C40B30/04;G01N33/48 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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