发明名称 |
CAROTENOID DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICALLY ACCEPTABLE ESTER OR AMIDE THEREOF |
摘要 |
The object of the present invention is to find a carotenoid compound that is excellent in water solubility. A carotenoid derivative having a formula (I):
wherein
X represents a carbonyl group or a methylene group, one of R 1 and R 2 represents (a) or (b) and the other represents (a), (b), (c) or a hydrogen atom:
(a): -CO-A-B-D wherein A represents an alkylene group an alkenylene group, etc., B represents a formula of -S(O) n - or a formula of -NR 4 CONR 5 - and D represents a hydrogen atom, a carboxy group, etc.,
(b): -CO-E-F wherein E represents an alkylene group or a formula of -NR 3 - wherein R 3 represents (a1) a hydrogen atom, (b1) an alkyl group etc., and F represents a sulfo group and
(c): -CO-G wherein G represents a hydrogen atom, an alkyl group, 1 etc.,
a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester or amide thereof. |
申请公布号 |
EP3147279(A1) |
申请公布日期 |
2017.03.29 |
申请号 |
EP20150795815 |
申请日期 |
2015.05.20 |
申请人 |
Fuji Chemical Industry Co., Ltd. |
发明人 |
FUJITA, Takashi;KOBAYASHI, Satoshi;SHINOHARA, Ryoma;NISHIDA, Yasuhiro;TAKAHASHI, Jiro |
分类号 |
C07C403/24;A61K31/22;A61K31/27;A61K31/4178;A61P3/04;A61P3/06;A61P9/04;A61P9/12;A61P21/00;A61P25/18;A61P25/24;A61P25/28;A61P27/00;A61P27/02;A61P27/06;A61P29/00;A61P35/00;C07D233/61 |
主分类号 |
C07C403/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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