Systems and methods for transfer of liquid samples

摘要

A system for preparing biological sample contains a body including a proximal side and a distal side, a plurality of mandrels, a plurality of resilient elements, a plurality of fluid dispensers, and one or more samples. The mandrels are moveably positioned within the body, where each resilient element engages a respective one of the mandrels. Each of the fluid dispensers is configured to engage a distal end of a corresponding one of the mandrels. Each sample comprises a solution containing one or more nucleic acid sequences contained within at least one of the fluid dispensers.

主权项

1. A loading system for dispensing one or more sample solutions containing at least one nucleic acid sequence, the system comprising:
a frame; a resilient element comprising a base and a plurality of non-linear elements, the base being fixed relative to the frame; a plurality of mandrels moveably positioned within the frame, each of the mandrels comprising a distal end configured to receive a fluid dispenser for dispensing one or more solutions containing one or more nucleic acid sequences; wherein each non-linear element engages a respective mandrel of the plurality of mandrels such that movement of the respective mandrel causes the respective non-linear element to exert a force on the respective mandrel, wherein the force is non-linear with a variation in a distance between the distal end of the respective mandrel and the base.