发明名称 |
Platform drug delivery system utilizing crystal engineering and theanine dissolution |
摘要 |
A platform drug delivery system and a method of improving the delivery of low solubility pharmaceuticals utilizing crystal engineering and Theanine dissolution resulting in enhanced bioactivity, dissolution rate, and solid state stability. |
申请公布号 |
US9603937(B2) |
申请公布日期 |
2017.03.28 |
申请号 |
US201514642191 |
申请日期 |
2015.03.09 |
申请人 |
Theaprin Pharmaceuticals Inc. |
发明人 |
Brittain Harry G.;Felice Philip V. |
分类号 |
A61K47/18;A61K47/48;A61K31/704;A61K31/13;A61K31/137;A61K31/192;A61K31/198;A61K31/277;A61K31/4045;A61K31/4164;A61K31/4196;A61K31/426;A61K31/43;A61K31/445;A61K31/4745;A61K31/48;A61K31/496;A61K31/4985;A61K31/506;A61K31/522;A61K31/536;A61K31/545;A61K31/546;A61K31/549;A61K31/573;A61K31/635;A61K31/7048;A61K31/7072;A61K38/12 |
主分类号 |
A61K47/18 |
代理机构 |
Nataro, Michalos & Zaccaria P.C. |
代理人 |
Nataro, Michalos & Zaccaria P.C. |
主权项 |
1. A cocrystal of
L-theanine; and doxorubicin, wherein said cocrystal is characterized as having an X-ray powder diffraction pattern with peaks (2θ) at 13.6, 18.2, 19.8, 22.0, 22.5, 25, and 38.2 degrees. |
地址 |
Hauppauge NY US |