发明名称 Derivatives of hemin with antibacterial and antiviral activity
摘要 The invention relates to hemin derivatives of general formula (I), preparing and use thereof as antibacterial and/or antiviral agents, including, as a component in a pharmaceutical compositions. Advantages of the antibacterial and antiviral agents based on the hemin derivatives are in their biocompatibility, biodegradability, a high efficacy against resistant bacteria and widespread viruses which are dangerous to humans, and the lack of toxicity.;
申请公布号 US9605013(B2) 申请公布日期 2017.03.28
申请号 US201214358998 申请日期 2012.11.15
申请人 OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU “PHARMENTERPRISES” 发明人 Nebolsin Vladimir Evgenievich;Zheltukhina Galina Alexandrovna;Okorochenkov Sergei Alexandrovich
分类号 C07D487/22;C07K14/795;A61K31/555;A61K38/00;C07F15/02;C07K5/062;C07K5/072 主分类号 C07D487/22
代理机构 Banner & Witcoff, Ltd. 代理人 Banner & Witcoff, Ltd.
主权项 1. A compound of formula (I)wherein R1 is selected from the group consisting ofR2 is the same as R1;Men+ is Fe2+ or Fe3+; Hal− is F−, Cl−, Br− or I−,or a pharmaceutically acceptable salt thereof.
地址 Moscow RU