发明名称 |
Derivatives of hemin with antibacterial and antiviral activity |
摘要 |
The invention relates to hemin derivatives of general formula (I), preparing and use thereof as antibacterial and/or antiviral agents, including, as a component in a pharmaceutical compositions. Advantages of the antibacterial and antiviral agents based on the hemin derivatives are in their biocompatibility, biodegradability, a high efficacy against resistant bacteria and widespread viruses which are dangerous to humans, and the lack of toxicity.; |
申请公布号 |
US9605013(B2) |
申请公布日期 |
2017.03.28 |
申请号 |
US201214358998 |
申请日期 |
2012.11.15 |
申请人 |
OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU “PHARMENTERPRISES” |
发明人 |
Nebolsin Vladimir Evgenievich;Zheltukhina Galina Alexandrovna;Okorochenkov Sergei Alexandrovich |
分类号 |
C07D487/22;C07K14/795;A61K31/555;A61K38/00;C07F15/02;C07K5/062;C07K5/072 |
主分类号 |
C07D487/22 |
代理机构 |
Banner & Witcoff, Ltd. |
代理人 |
Banner & Witcoff, Ltd. |
主权项 |
1. A compound of formula (I)wherein R1 is selected from the group consisting ofR2 is the same as R1;Men+ is Fe2+ or Fe3+; Hal− is F−, Cl−, Br− or I−,or a pharmaceutically acceptable salt thereof. |
地址 |
Moscow RU |