发明名称 Histone demethylase inhibitors
摘要 Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.
申请公布号 US9604961(B2) 申请公布日期 2017.03.28
申请号 US201314650241 申请日期 2013.12.05
申请人 Celgene Quanticel Research, Inc. 发明人 Nie Zhe;Stafford Jeffrey Alan;Veal James Marvin;Wallace Michael Brennan
分类号 C07D401/04;C07D405/14;C07D401/14;A61K31/44;A61K31/4439;A61K31/444 主分类号 C07D401/04
代理机构 Wiley Rein LLP 代理人 Wiley Rein LLP
主权项 1. A compound, or a pharmaceutically acceptable salt thereof, selected from:
地址 San Diego CA US