发明名称 Uses of orvepitant
摘要 This invention relates to the new use of the compound (I) or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing it for the treatment of pruritus and to combinations for such a use.;
申请公布号 US9603849(B2) 申请公布日期 2017.03.28
申请号 US201314426620 申请日期 2013.10.09
申请人 NERRE THERAPEUTICS LIMITED 发明人 Ratti Emiliangelo;Trower Michael
分类号 A61K31/4985;A61K31/495 主分类号 A61K31/4985
代理机构 Silvia Salvadori, P.C. 代理人 Silvia Salvadori, P.C. ;Salvadori Silvia
主权项 1. A method of treatment of chronic pruritus, wherein the pruritus is due to or associated with inflammatory dermatoses selected from atopic dermatitis/eczema, psoriasis, irritant/contact dermatitis, irritant/contact eczema, urticarial, dry skin, adverse drug reactions, scars, pruritus ani, pruritus scroti, pruritus vulvae and invisible dermatosis said method comprising administering to a human in need thereof 2-(R)-(4-Fluoro-2-methyl-phenyl)-4-(S)-((8aS)-6-oxo-hexahydro-pyrrolo[1,2-a]-pyrazin-2-yl)-piperidine-1-carboxylic acid [1-(R)-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methylamide or a pharmaceutically acceptable salt thereof.
地址 Stevenage Herts GB