| 摘要 |
The invention relates to a method for producing a mono-N-alkyl piperazine of formula (I), where R1 represents C1 to C5 alkyl or 2-(2-hydroxy-ethoxy) ethyl, by reacting diethanolamine (DEOA) of formula (II) with a primary amine of formula H2N-R1 (III) in the presence of hydrogen and a supported catalyst containing metal. The catalytically active mass of the catalyst, before reduction of the latter using hydrogen, contains oxygenic compounds of aluminum, copper, nickel and cobalt and between 0.2 and 5.0 wt. % oxygenic compounds of tin, calculated as SnO, and the reaction is carried out in the liquid phase at an absolute pressure ranging from 95 to 145 bar. |
