发明名称 |
SUBSTITUEREDE BENZOAZEPINER SOM MODULATORER AF TOLL-LIGNENDE RECEPTORER |
摘要 |
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease. |
申请公布号 |
DK2663555(T3) |
申请公布日期 |
2017.03.27 |
申请号 |
DK20120733896T |
申请日期 |
2012.01.12 |
申请人 |
VentiRx Pharmaceuticals, Inc.;Array Biopharma, Inc. |
发明人 |
DOHERTY, George A.;LYSSIKATOS, Joseph P.;YANG, Hong Woon;HOWBERT, James, Jeffry;HERSHBERG, Robert;EARY, Charles Todd;Groneberg, Robert D.;JONES, Zachary;BURGESS, Laurence E. |
分类号 |
A61K31/55;A61P37/00;C07D223/16;C07D243/14;C07D401/12;C07D487/04 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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