Yeast Display Systems

摘要

The present invention relates to the field of protein display libraries and library screening, In preferred embodiments, the present invention provides a three component system for display comprising a cell surface molecule, an adapter molecule and a display molecule.

主权项

1. A host cell comprising:
(a) a cell surface molecule attached to the surface of the cell, (b) an adapter molecule comprising a first binding site and a second binding she, and (c) a display molecule comprising a modified polypeptide; wherein the first binding site binds specifically to the cell surface molecule and cannot bind to the display molecule and the second binding site binds specifically to the display molecule and cannot bind to the cell surface molecule, and wherein the adapter molecule is not a component of the modified polypeptide.