METHOD FOR PRODUCING STABILIZED AMORPHOUS CALCIUM CARBONATE

摘要

Provided is a method for preparing a stable amorphous calcium carbonate (ACC), which can be obtained either in suspension or as a powder. The method comprises stepwise combination of a soluble calcium salt, a soluble carbonate, a first and second stabilizer, and a water miscible organic solvent as described herein. The present invention further relates to stable ACC suspensions and dry powders produced by the method of the present invention.

主权项

1. A suspension of a stabilized amorphous calcium carbonate (ACC) prepared by a method, the method comprising:
combining an aqueous solution including a soluble calcium salt and a first stabilizer with an aqueous solution comprising a soluble carbonate so as to form an ACC suspension; and adding a water miscible organic solvent and a solution including a second stabilizer, substantially simultaneously or sequentially in any order, thereby obtaining a stabilized suspension of ACC; wherein the first stabilizer and the second stabilizer are the same or different; wherein a total amount of the first and second stabilizers constitutes up to about 12 weight % (wt %) of the suspension; and wherein the suspension of ACC includes at least about 5 wt % of the water miscible organic solvent.