PREDICTION AND RECOGNITION OF ACUTE KIDNEY INJURY AFTER SURGERY

摘要

Systems, kits, and methods for predicting the risk of an adverse event related to acute kidney injury AKI as a consequence of a surgical intervention in a subject. Embodiments of the system and methods include means and steps for determining an amount of liver-type fatty acid binding protein (L-FABP) in a sample, such as a urine-sample of a subject; comparing the amounts of the L-FABP with a reference amount, and predicting the risk of an adverse event related to acute kidney injury as a consequence of surgical intervention in the subject.

主权项

1. A method for diagnosing acute kidney injury in a subject, comprising:
determining an amount of liver-type fatty acid binding protein, or a variant thereof, in a portion of a sample of a subject; comparing the amount of liver-type fatty acid binding protein, or variant thereof, determined in said step of determining to a liver-type fatty acid binding protein reference amount; and providing a diagnosis of acute kidney injury in the subject if the amount of liver-type fatty acid binding protein, or the variant thereof, determined in said step of determining is greater than the liver-type fatty acid binding protein reference amount.