发明名称 |
DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE |
摘要 |
Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. The bioavailability of zoledronic acid can be enhanced by administering the zoledronic acid in the disodium salt form. |
申请公布号 |
US2017079995(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
US201615365748 |
申请日期 |
2016.11.30 |
申请人 |
ANTECIP BIOVENTURES II LLC |
发明人 |
Tabuteau Herriot |
分类号 |
A61K31/675;A61K9/00 |
主分类号 |
A61K31/675 |
代理机构 |
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代理人 |
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主权项 |
1. A method of delivering zoledronic acid to the blood of a human being comprising orally administering zoledronic acid in the disodium salt form to a human being in need of treatment with zoledronic acid, wherein the zoledronic acid in the disodium salt form is orally administered at least twice, wherein the human being is instructed not to eat or drink for at least 1 hour before and at least 1 hour after the zoledronic acid in the disodium salt form is orally administered, and wherein the zoledronic acid in the disodium salt form is orally administered in a manner that results in a bioavailability of zoledronic acid in the human being of 1.3% to about 4%. |
地址 |
New York NY US |