主权项 |
1. A method for treating an infection by the HPV 6 or HPV 11 papilloma virus comprising the administration to a patient in need thereof of an efficient quantity of a compound of formula (I): as well as their stereoisomers, wherein: G1 is a bond or a saturated or unsaturated, branched or linear hydrocarbon chain comprising 1-4 carbon atoms, optionally substituted with one or two alkyl groups, G2 is agroup, the N(R) moiety being bound to the nitrogen carrying the groups B and AG1, wherein:
R is hydrogen atom, an alkyl, a haloalkyl group or a radical selected from the group consisting of carbamate, acetyl, dialkylaminomethyl and —CH2—O—CO— Alk,G is a bond or a saturated or unsaturated, linear or branched hydrocarbon chain comprising 1-4 carbon atoms, optionally substituted with one or two alkyl groups,W is an oxygen, sulfur or NH, R1 and R2 are either identical or different, each represent a group selected from the group consisting of a hydrogen atom, a halogen atom, a hydroxyl, thio, alkoxy, haloalkoxy, alkylthio, haloalkylthio, amino, monoalkylamino, dialkylamino, cycloalkyl, alkyl, and haloalkyl group, R3 is an acid group or a bioisostere of the acid function selected from the group consisting of a tetrazole, phosphonate, phosphonamide, sulfonate and sulfonamide, A is an aryl, cycloalkyl, cycloalkenyl group or a heterocycle, each optionally substituted, and B is an aryl group or a 6-membered heterocycle, each optionally substituted, as well as their pharmaceutically acceptable salts. |